Alzheimer's disease (AD) is characterised, not only by cognitive deficits and
neuropathological changes, but also by several non-cognitive behavioural symptoms that
can lead to a poorer quality of life. Circadian disturbances in core body temperature and
physical activity are reported in AD patients, although the cause and consequences of these
changes are unknown. We therefore characterised circadian patterns of body temperature
and activity in male triple transgenic AD mice (3xTgAD) and non-transgenic (Non-Tg) control …